Condition

AGE

DCS

CO Poisoning

Gas gangrene

Crush injury, compartment syndrome

Problem wounds

Exceptional blood loss

Intracranial abcess

Necrotizing soft tissue infections

Refractory osteomyelitis

Radiation injury

Skin flaps

Burns

Action

Pressure effects

1, 2, 3, 5, 98, 99

1, 2, 3

Oxygen diffusion

1, 2, 3

1, 2, 3, 100

Tissue hyperoxygenation

4, 5

4, 105

6, 7, 8, 101, 102

4, 9, 10, 27

11, 12

4, 109, 110, 112 113

23, 24

26, 60

9, 25, 26, 27

61, 62, 63, 66

70

13,14 15,16 30,31

89, 90

Vascoconstriction

9, 33, 106, 107

29,33

21

9, 33

28, 33

Down-regulation of cytokines

37

37, 38

39, 103

41,48, 49

74,,75

55

20

59

41, 50

67,68

85, 86, 87, 88

34, 35 36,91,93

Up-regulation of growth factors

19,76,77, 78,80

19, 51, 52, 53, 54, 79

22

64,65

69, 81

81, 82, 83, 84

92, 94 95, 96

Leukocyte effects

18, 40

18

18, 104

26, 43 44

18, 108

56, 57

43,44

43, 44

58

71,72

17, 18, 32 108

18, 36

Antibacterial effects

45,46 47,48

111, 112

45, 46, 47, 48

45, 46 47, 48

45,46 47,48

97

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29

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30

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50

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53

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54

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55

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59

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60

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62

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63

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109

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110

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111

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112

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113

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